Home     |     Company     |     Services     |     Products     |     Expertise     |     Contact     |     Impressum
 

Products

genmedics supplies a large variety of specialty products for scientific and industrial use. For the production we mainly use the expression in food-grade Staphylococcus carnosus. Because of its food-grade status the Staphylococcus carnosus is a very versatile and safe system for the expression of therapeutic peptides, proteins and plasmid DNA. This system, naturally, can also be used for the expression of custom-made substances.

Peptide Antibiotics

Gallidermin (expressed in Staphylococcus gallinarum) is an anti-infectivum useful for the topical treatment of skin infections like acne and mastitis, skin or mucus colonisation with pathogens, or therapy of recalcitrant infectious agents in endocarditis and urinary tract infections. The special advantage of Gallidermin lies in its bactericidal activity and ability to act against resting bacteria, thus making Gallidermin a promising alternative antibiotic.

Peptide Pheromones

genmedics distinguishes itself within the industry with its expertise in the area of peptide pheromones. These peptide pheromones (US-patent #6660835) interfere with cell communication of staphylococci and may also have therapeutic potential:
- Thiolactones
- Lactones
- Lactams

Enzymes for Research and Industry

- Lysostaphin (Cell wall lytic enzymes)
- Amidases (Cell wall lytic enzymes)
- Glucosaminidases (Cell wall lytic enzymes)
- Proteases
- Lipases
- Aldolase (fructose-1,6-phosphate specific)
- Beta-galactosidase

Cellwall Structures for Research and Industry

- Murein sacculi as well as soluble murein fragments from staphylococci and Escherichia coli bacteria for    the study of murein biosynthesis, as substrates for enzyme assays, and immune modulators

Plasmid Vectors

- Plasmid vectors for gene therapy able, among other capabilities, to express the human monocyte    chemoattractant protein-1 (MCP-1)

Recombinant Proteins Produced in Food-Grade Staphylococcus carnosus

- Single chain antibodies
- Human calcitonin precursor
- Human growth hormone
- Insulin

In addition, genmedics is experienced in expressing and producing recombinant proteins in Escherichia coli.

 

Active compounds against
multiresistant strains from
our products portfolio


 
   
2013 TEXTILCHEMIE DR. PETRY GMBH